The Role of Routine Biochemical Parameters in Prediction of Early Prognosis in Patients with Subarachnoid Hemorrhage Due to the Middle Cerebral Artery Aneurysm

Objective: There are few studies in literature showing prognostic markers of patients with aneurysm related subarachnoid hemorrhage (SAH). The aim of this study was to predict early prognosis of patients who developed SAH due to the middle cerebral artery aneurysm using simple blood biochemistry test results. Material and Methods: Age, gender, Glasgow Coma Scale (GCS) and Fisher grading scores, length of stay in the Intensive Care Unit (ICU) and in hospital and Glasgow Outcome Scale (GOS) scores, hemoglobin values, leukocyte, neutrophil, lymphocyte, platelet, eosinophil, basophil counts, neutrophil-lymphocyte and platelet-lymphocyte ratios, serum glucose, aspartate aminotransferase, alanine aminotransferase, C-reactive protein, blood urea nitrogen, creatinin, sodium and potassium levels were evaluated. Results: This study consisted of 12 patients (male=5). In female patients, serum sodium and creatinine values were lower and glucose values and Fisher grading score were higher than in male patients. A negative correlation was found between GCS and length of stay in ICU and in hospital. A positive correlation was found between Fisher's grading score and gender and between Fisher's grading score and length of stay in ICU, and a negative correlation was found between Fisher's grading score and hemoglobin, creatinine, and sodium values. A positive correlation was found between GOS and GCS scores, whereas a negative correlation was found between GOS and Fisher's grading score, length of stay in ICU and length of stay in hospital. Conclusion: It was found that early prognosis of patients with high GCS scores could be better. On the other hand, it was predicted that the early prognosis of the patients who had a high Fisher rating score and who were in the intensive care unit and hospital for a long time could be poor. It was thought that hemoglobin, serum sodium and creatinine levels could have indirect effects on the early prognosis of patients