Gd(OTf)3 Catalyzed Nucleophilic Ring Opening of Donor-Acceptor Cyclopropanes with N-Methyl Indole

In this study, homo-Michael addition of N-methyl indole into various donor-acceptor (DA) cyclopropanes was performed using Gd(OTf)3 as a catalyst. In the reaction, high pressure and high catalyst ratio were not required. All of the DA cyclopropanes used as substrates showed high reactivity without regard to their structure under optimizing method conditions. For this reason, a new one is added to the mild conditions required in the literature for similar studies. The structure characterization of the synthesized compounds was carried out by 1H, 13C NMR and High Resolution Mass Spectroscopy (HRMS)