Green Chemistry Metrics: Calculation of Green Chemistry Metrics of Biginelli Compounds Synthesized Under the Catalyst and Catalyst-Free Reaction Conditions

In this study, green chemistry metrics such as atom economy, environmental factor (E-factor), carbon efficieny, reaction mass efficiency and mass intensity of synthesized twelve Biginelli compounds under MgBr2 or MgCl2·6H2O catalysed, solvent-free and catalyst-free with solvent (EtOH) conditions were calculated. All green chemistry metrics results were compared and the best green chemistry reaction conditions and green metrics for twelve Biginelli compounds were determined