Comparison of Parameters Elevated Because of Stess in ？nguinal Hernia Sugeries Operated with Open and Closed Techniques

Abdominal Wall hernias are the protrusion of viscera, abdominal wall muscles and fascia through an opening in the mesentery or around the viscera. In this study, we aimed at comparing blood creatinine phosphokinase (CPK), interleukin-1 (IL-1) (its release also increases in trauma), interleukin-6 (IL-6), glucose levels and white blood cell (WBC) counts between laparoscopic total extraperitoneal (TEP) inguinal hernia repair surgery and open inguinal hernia repair. A total of 40 patients who underwent inguinal hernia repair surgery were included in the study. 20 out of 40 patients underwent a TEP hernia repair and 20 underwent open inguinal hernia repair. Blood samples were taken from the antecubital vein before the surgery, during the surgery, at hour 2 and hour 24 after the surgery and CPK, IL-1, IL-6, glucose levels and WBC counts were measured. The comparisons between laparoscopic inguinal hernia repair and open inguinal hernia repair revealed that CPK levels were significantly higher in the TEP group than the open surgery group in blood samples collected during the surgery (p=0.047) and at hour 2 (p=0.001) and hour 24 after the surgery (p=0.003). During the surgical procedure, blood glucose concentrations were significantly higher than the pre-operative values in both open and TEP surgery groups. A significant decrease (p=0.004) was observed in blood glucose concentrations at hour 2 after the surgery in the TEP group, while a significant reduction was observed in blood glucose concentrations in the open surgery group only 24 hours after the surgery (p=0.037). No significant differences were observed between the open repair and TEP repair groups in blood glucose concentrations (p=0.05). No significant differences were observed between the open repair and TEP repair groups in WBC counts (p>0.05). No significant differences were observed between the open hernia repair and TEP groups in IL-1 and LI levels at hour 2 and hour 24 after the surgery (p>0,05). Blood CPK levels may increase after surgical procedures in correlation with the severity of muscle injury. CPK levels were higher in patients who underwent TEP hernia repair surgery than the patients who underwent open surgery. The increases in blood glucose concentrations and WBC counts correlated with the severity of injury and the increase stopped in the TEP group earlier than the Open repair group. In conclusion, laparoscopic TEP hernia repair and open hernia repair did not significantly differ from each other in the severity of surgical injury, based on the parameters assessed in this study. None of