GC/MS Analysis and Antimicrobial Activity of The Volatile Compounds From Dianthus carmelitarum Reut. ex Boiss and Dianthus calocephalus Boiss. Grown in Turkey

The chemical composition of the essential oils of Dianthus carmelitarum Reut. ex Boiss. and Dianthus calocephalus Boiss. were identified by GC-FID and GC-MS. Essential oils of D. carmelitarum and D. calocephalus were obtained from the whole part of fresh plant by Clevenger-type distillation. Analyses of the essential oils gave 40 and 35 compounds, constituting over 86.58% and 76.45% in the total, respectively. Main components in D. carmelitarum were heneicosane (11.69%), docosane (10.52%), tetracosane (9.20%) and pyhtol (4.62%). Whereas, 4,4-dimethyl-2-pentene (17.65%), phytol (15.47%), pentacosane (4.38%) and hexahydrofarnesyl acetone (3.08%) were the major constituents in D. calocephalus. Antimicrobial activity of the essential oils obtained from D. carmelitarum and D. calocephalus were evaluated against nine gram positive, gram negative bacteria and the yeast-like fungi using disc diffusion and broth microdilution methods. The essential oils of D. carmelitarum and D. calocephalus showed good antimycotic activity against Candida albicans having the MIC values of 668 μg/mL and 1041 μg/mL, respectively