Autoimmune Marker Prevalence in Pityriasis Rosea Patients

Introduction and Aim: Pityriasis rosea (PR) is an acute, self-limited papulo-squamous disorder which was described in 1798, firstly. The etiology of PR is unknown, infectious etiology has been the most investigated subject but no exact infectious origin is identified to date. Autoimmunity, genetic predisposition and atopi are the other subject matters which have been investigated. The prevalence of anti-nuclear antibody (ANA) was investigated in PR patients to evaluate the potential role of autoimmunity in etiopathogenesis of PR. Materials and method: This study is designed to compare the prevalence of serum anti-nuclear antibody (ANA) in PR patients and healthy volunteers. Results: ANA prevalence was 8,7% in PR group, where as it was 0, in the control group (p<0.05) . Conclusion: ANA prevalence of 8,7% among PR patients is statistically significant, but this rate is similar with the expected ANA prevalence among healthy population which is 4-5%. Further larger studies are needed to evaluate the part of autoimmunity in etiopathogenesis of PR