Some 2,5-Disubstitue-1,3,4-Oxadiazoles as New Antioxidants

Many heterocyclic compound, a pharmacologically used as the starting compound for the synthesis of new structures which are important. Groups of these azole compounds, due to their various biological activities, in recent years have become common classes of compounds synthesized. Heterocyclic compounds containing five-membered ring, compounds of pharmacological class have entered popular in recent years due to properties. In this study, antioxidant activities of some 2,5-disubstitue-1,3,4-oxadiazoles (1-3) were evaluated for according to ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities and iron reducing power capacity. The obtained results showed that the synthesized compounds (1-3) had effective antioxidant activities