The frequency of the incidental prostate cancer of the patients that were diagnosed as bladder cancer and underwent radical cystectomy and the oncological outcomes

Objective: The aim of this study was to evaluate the incidence, histopathological results and oncologic outcome of patients who underwent radical cystoprostatectomy for bladder tumors and detected incidental pros- tate adenocarcinoma. Materials-Methods: 190 patients who were not proved to have preoperative prostate cancer and underwent radical cystoprostatectomy and diagnosed as prostate cancer as a second cancer between January 2010 and December 2017 were included in this study. Patients were randomly divided into two groups those with and without incidentally prostate cancer. Both groups were compared in terms of age, preoperative PSA value, body mass index, stage and grade of bladder tumor, accompanying of carcinoma in situ, surgical margin positivity, lymph node involvement and overall survival retrospectively. Results: The clinical and the histopathological features of the patients were summarized on Table 1 and Table 2. Fourtthree of the 190 patients (22.6 %) were detected prostate adenocarcinoma by the histopathological evaluation. The mean preoperative PSA level was 5.38 ng / ml in patients who had prostate cancer and the mean PSA value in the group without prostate cancer was 2.72 ng/ ml (p=0,015). The mean duration of follow-up was 26 (3-74) months. The biochemical recurrence was detected at 5 (11.6%) patients during the follow-up. When the two groups were evaluated for 5-year survival rates that was 61% for patients with prostate cancer and 53% for patients without prostate cancer (p=0.471). Conclusion: The incidence of incidental prostate cancer after radical cystoprostatectomy increases with age but does not affect the prognosis of patients. In particular, the patients with locally advanced prostate cancer were needed to follow carefully and regularly