Pancytopenia, Acute Renal Failure and ？leus Due to Salmonella Paratyphi A: Case Report

Although Salmonella species are are one of the common bacterial causative microorganism of gastroenteritis in our country, but also can cause different type of infections such as typho-paratyphoid, bacteriemia, metastatic infections and chronic carriage besides gastroenteritis. In this case report, we aimed to a rare offer a case of pancytopenia, acute renal failure and ileus due to Salmonella paratyphi A. A 77-year-old man without history of known chronic disease other than hypertension, presented to the emergency department with fever, nausea, vomiting, abdominal pain and diarrhea. The patient was hospitalized with the diagnosis of acute gastroenteritis, acute renal failure and pancytopenia. Blood and stool cultures were taken and ciprofloxacin treatment was started empirically. With antibiotic treatment, the patient's condition started improving in terms of resolution of diarrhea and pancytopenia. However, the patient was transferred to the intensive care unit on the 4th day of ospitalization as development of ileus and confusion. Salmonella-Shigella bacterial growth was not observed in the patient's stool culture, but ampicillin resistant, ceftriaxone, cefotaxime, trimethoprim/sulfamethoxazole, ciprofloxacin susceptible Salmonella paratyphi A was detected in his blood culture. The patient's antibiotic treatment was not altered. The patient had received ciprofloxacin therapy with renal dose of 2x200 mg/day for 2 weeks as intravenously. The patient's acute renal failure table resolved without hemodialysis. The patient was transferred to our clinic from the intensive care unit and the patient was discharged by healing