The Histopathological Features of Colorectal Carcinomas

Colorectal carcinomas are one of the most common cancers after skin cancers and one of the most common causes of cancer related deaths worldwide. Various histopathological features, which may affect long-term prognosis after surgery, have been researched to explain the different clinical courses of patients at the same stage in colorectal carcinomas. Putting forth the histopathological profile of this type of tumors may affect patient-based foresights. We aimed to define the histopathological features of colorectal carcinomas diagnosed in our center. A total of 55 patients diagnosed as colorectal carcinoma between January 2013 and January 2017 is included in this study. Tumors showing special types which are presented by different clinical course such as mucinous carcinomas, tumors with neuroendocrine differentiation are excluded in order to make homogenous groups. The demographic and pathological features were obtained from pathology records. Statistical analysis was done by SPSS v20.0. When the relation between the major histopathological features, which are thought to be associated with poor prognosis such as pathological stage (Pt), involvement of the regional lymph nodes, lymphovascular and perineural invasion, tumor grade and distant metastasis, was examined, it was found out that the relation was significantly associated with prognosis. We think that putting forth the characteristic histopathological features may help predicting the prognosis of the patients at the same stage and may enlighten the way of developing new patient-based treatment modalities