The relationship between metabolic syndrome and vitamin D levels in patients with schizophrenia

Purpose: Metabolic Syndrome is an important risk factor for early death in patients with psychotic disorders. In previous studies, the relationship between metabolic syndrome and sociodemographic characteristics, antipsychotic use in patients with psychotic disorder has been investigated. In this study, it was aimed to determine the relationship between vitamin D levels, Positive and Negative Syndrome Scale scores, the use of antipsychotics and sociodemographic data in metabolic syndrome in patients with schizophrenia. Materials and Methods: A total of 119 patients with schizophrenia who were treated at inpatients clinics of ？ukurova University Faculty of Medicine Department of Psychiatry were included in this retrospective study. Thirtyone of 119 patients with schizophrenia were diagnosed with metabolic syndrome. Sociodemographic data, duration of disorder, number of hospitalizations, Positive and Negative Syndrome Scale scores, vitamin D blood levels, HDL, triglyceride, glucose, HBa1c, arterial blood pressure, waist circumference, body mass index were measured. Results: Of the patients included in the study, 63 were female and 56 were male. Vitamin D levels were lower in 63 patients. Significant differences were found in HDL, arterial blood pressure, fasting blood glucose, triglyceride, waist circumference, body mass index values among those with and without metabolic syndrome. These values are not included in the logistic regression analysis because they are metabolic syndrome diagnostic criteria for the National Cholesterol Education Program Adult Treatment Panel III. Simple linear regression and logistic regression analysis showed that the disease year and patient ages were significantly higher and vitamin D levels were significantly lower in the metabolic syndrome group (p <0.05). Conclusion: In this study, it has been shown that vitamin D blood level should be taken into account in the factors that increase the risk of metabolic syndrome