Solvent-Free Biginelli Condensation using Tungstate Sulfuric Acid: a Powerful and Reusable Catalyst for Selective Synthesis

Tungstate sulfuric acid (TSA) has been prepared and used as a recyclable catalyst for the Biginelli syn-thesis of some biologically active quinazolinones/thiones under solvent-free conditions. This method has advantages such as the avoidance of organic solvents, high yield of pure products, short reaction times, and operational simplicity. ？ 2014 BCREC UNDIP. All rights Received: 28th April 2014; Revised: 15th May 2014; Accepted: 26th May 2014 [ How to Cite: Nasab, R.R., Karami, B., Khodabakhshi, S. (2014). Selective Solvent‐free Biginelli Condensation using Tungstate Sulfuric Acid as Powerful and Reusable Catalyst. Bulletin of Chemical Reaction Engineering & Catalysis, 9 (2): 142-154. (doi:10.9767/bcrec.9.2.6794.148-154)] [ Permalink/DOI: http://dx.doi.org/10.9767/bcrec.9.2.6794.148-154