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-  2019 

The ProTide Prodrug Technology: Where Next?

DOI: https://doi.org/10.1021/acsmedchemlett.8b00586

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Abstract:

High Resolution Image Download MS PowerPoint Slide The ProTide prodrug technology has proved very useful in the discovery of nucleotide therapeutics and has successfully led to two FDA-approved drugs. However, with the extensive application of this prodrug approach to nucleotides for nearly three decades, the intellectual property (IP) landscape is becoming congested and, to overcome this, new inventive applications of the ProTide prodrug technology are emerging

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