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-  2019 

Atorvastatin (Lipitor) by MCR

DOI: https://doi.org/10.1021/acsmedchemlett.8b00579

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Abstract:

High Resolution Image Download MS PowerPoint Slide A concise and convergent synthesis of the atorvastatin, the best-selling cardiovascular drug of all time, is presented. Our approach is based on an Ugi reaction, which shortens the current synthetic route and is advantageous over the published syntheses

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