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- 2019
Atorvastatin (Lipitor) by MCRDOI: https://doi.org/10.1021/acsmedchemlett.8b00579 Abstract: High Resolution Image Download MS PowerPoint Slide A concise and convergent synthesis of the atorvastatin, the best-selling cardiovascular drug of all time, is presented. Our approach is based on an Ugi reaction, which shortens the current synthetic route and is advantageous over the published syntheses
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