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-  2019 

Regulation of Actin Dynamics in the C. elegans Somatic Gonad

DOI: https://doi.org/10.3390/jdb7010006

Keywords: actin cytoskeleton, C. elegans, spermatheca, sheath, contractility

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Abstract:

Abstract The reproductive system of the hermaphroditic nematode C. elegans consists of a series of contractile cell types—including the gonadal sheath cells, the spermathecal cells and the spermatheca–uterine valve—that contract in a coordinated manner to regulate oocyte entry and exit of the fertilized embryo into the uterus. Contraction is driven by acto-myosin contraction and relies on the development and maintenance of specialized acto-myosin networks in each cell type. Study of this system has revealed insights into the regulation of acto-myosin network assembly and contractility in vivo. View Full-Tex

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