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- 2019
Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic ProgenitorsDOI: https://doi.org/10.1016/j.stem.2018.12.014 Abstract: ？ Aging alters the myogenic support of FAPs to MuSCs ？ Aged FAPs produce less matricellular WISP1 ？ FAP-derived WISP1 is required for MuSC expansion and commitment ？ Restoring WISP1 levels rejuvenates the myogenic potential of aged MuSC
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