Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells

？ Organoids support hematopoietic and T cell differentiation from human PSCs ？ Organoids support spontaneous positive selection of PSC-derived naive T cells ？ PSC-derived T cells are transcriptionally similar to primary conventional T cells ？ Naive, antigen-specific T cells are generated from TCR-engineered PSCs in organoid