Turning Meristems into Fortresses

TERMINAL FLOWER1 ( TFL1) was discovered from forward genetic studies in Arabidopsis thaliana and was found to regulate inflorescence indeterminacy by mutual repression of the floral meristem identity genes LEAFY ( LFY) and APETALA1 ( AP1). Recent analyses indicated that LFY rather acts as an activator of TFL1 and only indirectly represses TFL1 through AP1