Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

？ We define two multiplet errors in single-cell RNA-seq data: “embedded” and “neotypic” ？ Neotypic errors can lead to misidentification of cell types or transitional states ？ Scrublet code identifies neotypic doublets and predicts the overall doublet rate ？ The algorithm is tested against several experimental methods for labeling multiplet