|
- 2019
Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In VivoDOI: https://doi.org/10.1016/j.cels.2019.01.004 Abstract: ? Genome-scale in vivo CRISPR screens identified tumor-intrinsic factors of oncogenesis ? Prkar1a is a strong genetic driver of oncogenesis ? Prkar1a loss altered the transcriptome and proteome in immune responses ? Prkar1a mutation in cancer cells remodels the tumor microenvironmen
|