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-  2019 

Inflammation and Hypoxia: HIF and PHD Isoform Selectivity

DOI: https://doi.org/10.1016/j.molmed.2018.10.006

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Abstract:

Hypoxia signaling pathways are highly conserved between species and are ubiquitously expressed in mammalian cells. Activation of HIF has pleiotropic effects, and is under investigation as a potential therapeutic target in malignancy, ischemia, and inflammatory disease processes

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