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- 2019
A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell DifferentiationDOI: https://doi.org/10.1016/j.immuni.2019.02.004 Abstract: ? cRel drives B cell proliferation but blocks antibody-secreting cell differentiation ? In ASCs, RelA-induced Blimp1 represses cRel via binding the Rel enhancer ? NFκB dynamics transition cells across the bi-stable ABC-ASC differentiation network ? Multi-scale model of single-cell-fate decisions explains B cell population dynamic
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