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-  2019 

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells

DOI: https://doi.org/10.1016/j.immuni.2019.03.010

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Abstract:

? gH/gL antibodies in plasma neutralize EBV infection of B cells and epithelial cells ? EBV gH/gL or gH/gL/gp42 nanoparticles induce potent neutralizing antibody responses ? Vaccine-induced antibodies neutralize EBV infection of B cells and epithelial cells ? Vaccine-induced antibodies block virus-mediated cell fusion by targeting EBV gH/g

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