|
|
- 2019
FAT4 Fine-Tunes Kidney Development by Regulating RET SignalingDOI: https://doi.org/10.1016/j.devcel.2019.02.004 Abstract: ？ Fat4 mutant mice have duplex kidney defects due to ectopic bud formation ？ FAT4 functions non-autonomously in the mesenchyme to prevent kidney duplication ？ RET signaling is overactive in Fat4 mutants ？ FAT4 interacts with RET, perturbs RET-GFRA1-GDNF assembly, and reduces RET signalin
|
