Repurposing Kinetochore Microtubule Attachment Machinery in Neurodevelopment

Kinetochore-microtubule attachments are essential to direct proper chromosome segregation during cell division. In this issue of Developmental Cell, Cheerambathur et al. (2019) Cheerambathur D.K. Prevo B. Chow T.-L. Hattersley N. Wang S. Zhao Z. Kim T. Gerson-Gurwitz A. Oegema K. Green R. Desai A. The kinetochore-microtubule coupling machinery is repurposed in sensory nervous system morphogenesis. Dev. Cell. 2019; 48 ( this issue) : 864-872 Google Scholar and Zhao et al. (2019) Zhao G. Oztan A. Ye Y. Schwarz T.L. Kinetochore proteins have a post-mitotic function in neurodevelopment. Dev. Cell. 2019; 48 ( this issue) : 873-882 Google Scholar uncover an unexpected role in neuronal development, unrelated to cell division, for components of the highly conserved kinetochore-microtubule attachment complex