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-  2019 

Unexpected Friendship: Neutrophils Help Tumor Cells En Route to Metastasis

DOI: https://doi.org/10.1016/j.devcel.2019.04.021

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Abstract:

Circulating tumor cells (CTCs) contain metastatic precursors that can initiate new metastases. Recent work shows that association with neutrophils provides a proliferative advantage to CTCs, rendering them more competent in metastasis formation. The study identifies molecular players in CTC-neutrophil interactions, providing potential targets for disrupting formation of these deadly metastatic seeds

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