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OALib Journal期刊
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-  2019 

Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells

DOI: https://doi.org/10.1016/j.immuni.2019.03.002

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Abstract:

? CD69 ? CD8 + T cells in skin are recirculating memory cells ? TGF-β activation in skin is required for recirculating memory CD8 + T cell persistence ? The peripheral tissue environment shapes central and peripheral memory-T-cell pools ? Loss of recirculating memory T cells impairs host defense to skin infectio

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