Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization

？ Front protrusion and rear retraction are tightly coupled in migrating neutrophils ？ Mechanical model explains observed time lag of myosin accumulation at the cell rear ？ Dynamic myosin relocalization facilitates efficient cell turning ？ Myosin dynamics optimized to balance migration persistence and cell turning efficienc