Lifespan Extension in C. elegans Caused by Bacterial Colonization of the Intestine and Subsequent Activation of an Innate Immune Response

？ phm-2 encodes a SAFB protein conserved in mammals ？ phm-2 and eat-2 mutants have a defective pharynx and accumulate bacteria in the gut ？ Bacterial accumulation activates innate immunity and bacterial avoidance behavior ？ Bacterial avoidance leads to dietary restriction and delays agin