Scratching Beneath the Surface: Linking Skin Pathology with Food Allergy

A link between atopic dermatitis and food allergy has long been suspected but remains elusive. In this issue, Leyva-Castillo et al. (2019) Leyva-Castillo J. Galand C. Kam C. Bunton O. Gurish M. Musser M. Goldsmith J. Hait E. Nurko S. Brombacher F. et al. Mechanical injury promotes food anaphylaxiis by driving mast cell expansion. Immunity. 2019; 50 ( this issue) : 1262-1275 Google Scholar show how mechanical injury of the skin initiates a cascade of events that stimulate the expansion of mucosal mast cells and promote food anaphylaxis