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-  2019 

Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates

DOI: https://doi.org/10.1016/j.molcel.2019.01.001

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Abstract:

? The PRR pathway repairs ssDNA resulting from lesion-less replication stress ? Rad5 recruits TLS polymerases to stressed replication forks ? TLS polymerases repair ssDNA gaps in a mutagenic fashion ? Failure of Rad5 mutagenic repair leads to anaphase bridges and chromosome breakag

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