|
|
- 2019
The Long Non-Coding RNA lep-5 Promotes the Juvenile-to-Adult Transition by Destabilizing LIN-28DOI: https://doi.org/10.1016/j.devcel.2019.03.003 Abstract: ？ lep-5 acts in the heterochronic pathway to promote the larval-to-adult transition ？ lep-5 is a ～600 nt, highly structured lncRNA that is conserved across Caenorhabditis ？ Like the Makorin LEP-2, lep-5 promotes the degradation of LIN-28 protein ？ lep-5 may act as a scaffold to bring LEP-2 into close proximity with LIN-2
|
