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-  2019 

The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria

DOI: https://doi.org/10.1016/j.molcel.2019.01.041

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Abstract:

? NDP52 recruits upstream autophagy machinery to damaged Salmonella-containing vacuoles ? NDP52 trimerizes with the ULK subunit FIP200 and the TBK1 adaptor SINTBAD ? NDP52-dependent recruitment of FIP200-ULK and SINTBAD-TBK1 required for xenophagy ? Recruitment of ULK and TBK1 complexes promotes phagophore formation in sit

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