A-Tail of Telomerase RNA Maturation

In this issue of Molecular Cell, Roake et al. (2019) Roake C.M. Chen L. Chakravarthy A.L. Ferrell Jr., J.E. Raffa G.D. Artandi S.E. Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease. Mol. Cell. 2019; 74 ( this issue) : 688-700 Google Scholar define a feedforward kinetic pathway consisting of a cycle of oligoadenylation and deadenylation that regulates the production of mature human telomerase RNA