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- 2019
Continued Activity of the Pioneer Factor Zelda Is Required to Drive Zygotic Genome ActivationDOI: https://doi.org/10.1016/j.molcel.2019.01.014 Abstract: ? An N-terminal CRY2 tag allows rapid and reversible transcription factor inactivation ? Zelda activity is required throughout zygotic genome activation in Drosophila embryos ? Zelda is a pioneer factor that binds with sequence specificity to nucleosomal DNA ? Nucleosome binding by pioneer factors may enable genome access during S phas
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