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- 2019
Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon ProductionDOI: https://doi.org/10.1016/j.immuni.2018.12.013 Abstract: ? Loss of human OASL and mouse Oasl2 inhibits DNA virus infection ? OASL and Oasl2 inhibit cGAS-mediated IFN induction ? OASL specifically binds to cGAS to inhibit cGAS enzyme activity ? OASL binds to cGAS independently of double-stranded DN
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