Getting in LINE with Replication

Sultana et al. (2019) Sultana T. van Essen D. Siol O. Bailly-Bechet M. Philippe C. Zine El Aabidine A. Pioger L. Nigumann P. Saccani S. Andrau J.C. et al. The landscape of L1 retrotransposons in the human genome is shaped by pre-insertion sequence biases and post-insertion selection. Mol. Cell. 2019; 74 ( this issue) : 555-570 Abstract Full Text Full Text PDF Scopus (1) Google Scholar and Flasch et al. (2019) Flasch D.A. Macia á. Sánchez L. Ljungman M. Heras S.R. García-Pérez J.L. Wilson T.E. Moran J.V. Genome-wide de novo L1 retrotransposition connects endonuclease activity with replication. Cell. 2019; ( Published online April 4, 2019) 10.1016/j.cell.2019.02.050 Abstract Full Text Full Text PDF PubMed Scopus (2) Google Scholar determined integration patterns of human LINE-1 (long interspersed element-1) retrotransposons highlighting their interaction with DNA replication guided by their 5′-TTTT/AA-3′ integration motif and nucleotide biases in the genome