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OALib Journal期刊
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-  2019 

The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids

DOI: https://doi.org/10.1016/j.stem.2019.02.020

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Abstract:

? Inhibiting TAZ leads to increased levels of PS in AML cells ? TAZ and PS regulate AML stemness ? Reducing TAZ or increasing PS decreases AML stemness and activates TLR signaling ? Increasing PS is a potential therapeutic strategy for AM

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