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-  2019 

Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response

DOI: https://doi.org/10.1016/j.stem.2018.11.018

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Abstract:

? Patient stem cell-derived adipocytes differentially respond to antidiabetic drugs ? Drug responses are governed by genomic binding of PPARγ ? Patient-specific PPARγ genomic binding is controlled by genetic variation ? Genetic variation determines and predicts individual drug responsivenes

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