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- 2019
NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25DOI: https://doi.org/10.1016/j.chom.2019.02.013 Abstract: ? NLRP12 reduces interferon and cytokine responses to RNA viruses and 5′ppp-dsRNA ? NLRP12 associates with TRIM25 to disrupt Lys63 ubiquitination and activation of RIG-I ? Vesicular stomatitis virus (VSV) infection downregulates NLRP12 ? Myeloid-specific Nlrp12-deficient mice have increased resistance to VS
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