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-  2019 

Human Salivary Amylase Gene Copy Number Impacts Oral and Gut Microbiomes

DOI: https://doi.org/10.1016/j.chom.2019.03.001

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Abstract:

? High AMY1 copy number (CN) is associated with higher levels of Porphyromonas in saliva ? High AMY1-CN stool has more resistant starch degraders; drives more adiposity in GF mice ? Stool short-chain fatty acid levels are predictive of salivary amylase activity ? Upon diet standardization, gut microbiomes converged without eliminating difference

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