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-  2019 

Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination

DOI: https://doi.org/10.1016/j.molcel.2019.01.027

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Abstract:

? Human PCF11 enhances transcription termination and 3′ end processing, genome-wide ? PCF11 is substoichiometric to CPA complex due to autoregulation of its transcription ? PCF11 stimulates expression of closely spaced genes but attenuates other genes ? PCF11-mediated functions are conserved in vertebrates and essential in developmen

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