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-  2019 

Large-Scale, Quantitative Protein Assays on a High-Throughput DNA Sequencing Chip

DOI: https://doi.org/10.1016/j.molcel.2019.02.019

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Abstract:

? Generation of a massive peptide and protein array on a sequencing flow cell ? Direct measurement of binding and catalysis for ~10 5 protein mutational variants ? Patterns of amino acid mutation and cooperativity were analyzed in high throughput ? Discovery of high-avidity “superFLAG” epitope for the M2 anti-FLAG antibod

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