A Reverse TCA Cycle 2-Oxoacid:Ferredoxin Oxidoreductase that Makes C-C Bonds from CO2

？ A reverse TCA cycle enzyme that captures CO 2 ？ Native and substrate-bound structures reveal how substrates are recognized ？ Two-electron chemistry catalyzed by an enzyme with a single one-electron relay ？ Functional redox partners are small iron-sulfur cluster-bearing ferredoxin