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- 2019
Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal DementiaDOI: https://doi.org/10.1016/j.celrep.2018.12.085 Abstract: ? Tau mutations cause microtubule-mediated deformation of the nucleus in dementia ? Nuclear deformation results in defective nucleocytoplasmic transport ? Neuronal nuclei are deformed in the post-mortem frontotemporal dementia brain ? Disrupted nucleocytoplasmic transport is shared in multiple dementia
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