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-  2019 

Non-acylated Wnts Can Promote Signaling

DOI: https://doi.org/10.1016/j.celrep.2018.12.104

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Abstract:

? Several Wnts retain partial signaling activity when their acylation site is mutated ? Acylation-independent binding to FZD proteins can also be detected ? Wnts vary in their dependence on acylation for signaling function ? For a given Wnt, the dependence on acylation is context dependen

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