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-  2019 

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors

DOI: https://doi.org/10.1016/j.celrep.2019.01.094

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Abstract:

? We used human iPSCs to investigate how genetic variations affect cell behavior ? We integrate genomic, gene expression, and cell biology datasets ? We identify many mRNAs that correlated with modal cell behavior ? Outlier cell behavior correlates with genes containing rare deleterious SNV

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