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-  2019 

Simultaneous Live Imaging of Multiple Endogenous Proteins Reveals a Mechanism for Alzheimer’s-Related Plasticity Impairment

DOI: https://doi.org/10.1016/j.celrep.2019.03.041

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Abstract:

? FingR intrabodies enabled simultaneous live imaging of three endogenous proteins ? Aβ inhibits CaMKII trafficking after LTP-, but not LTD-inducing, stimuli ? The Aβ-induced block of CaMKII trafficking requires CaMKII activity ? Aβ induced internalization of the extrasynaptic, but not synaptic, NMDA recepto

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