Host-Specific Adaptive Diversification of Crohn’s Disease-Associated Adherent-Invasive Escherichia coli

？ Host-to-host transmission selects for AIEC with greater motility and acetate metabolism ？ Hypermotility mediates higher invasive and inflammatory host responses ？ Improved acetate utilization is a common trait for many hypomotile isolates ？ Crohn’s disease E. coli isolates also exhibit increased motility and acetate utilizatio