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-  2019 

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis

DOI: https://doi.org/10.1016/j.chom.2019.01.008

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Abstract:

? Bacteriophages target specific bacteria and mitigate bacterially driven colon cancer ? Phages activate phage-specific and non-specific IFN-γ mediated immune responses via TLR9 ? Phages exacerbate colitis, and TLR9/IFNγ blockade abrogates phage-mediated inflammation ? UC patient responses to fecal microbiota therapy correlate with Caurovirales abundanc

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